Methyl (6R*,6aR*,12bR*)-2,4-dimethyl-6-(2-methylphenyl)-1,3-dioxo-2,3,4,6a,7,12b-hexahydro-1H,6H-chromeno[4′,3′:4,5]pyrano[2,3-d]pyrimidine-6a-carboxylate
نویسندگان
چکیده
منابع مشابه
Methyl 6-(4-chlorophenyl)-2,4-dimethyl-1,3-dioxo-1,2,3,4,6,6a,7,12b-octahydrochromeno[4′,3′:4,5]pyrano[2,3-d]pyrimidine-6a-carboxylate
In the title compound, C(24)H(21)ClN(2)O(6), the two fused six-membered pyran rings adopt half-chair conformations. The dihedral angle between the pyrimidine ring and the chloro-phenyl ring is 51.55 (3)°. In the crystal, mol-ecules are linked by pairs of weak inter-molecular C-H⋯O hydrogen bonds, forming inversion dimers. A C-H⋯π inter-action is also observed.
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The title compound, C(22)H(19)NO(2), has potential for use as a new nonlinear optical material. Mol-ecules are almost planar. One C atom of the heterocyclic ring system is disordered over two positions; the site occupancy factors are 0.6 and 0.4.
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In the title compound, C(12)H(14)O(4), the two acet-oxy groups are inclined by 57.92 (5)° and 62.71 (6)° to the benzene ring. An inter-molecular C-H⋯O inter-action involving the two acet-oxy groups generates a centrosymmetric dimer via an R(2) (2)(16) ring motif.
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Objective- Breast cancer is one of the most serious problems in oncology. Alkaloids pyrrolizidine are widely found in nature and exhibited versatile biological activities. The aim of the present study was to assess anti-tumor activity of methyl 1,3-dioxo-1,1',2',3,5',6',7',7a'-octahydrospiro[indene-2,3'-pyrrolizidine]-2'-carboxylate (6) on 7,12 dimethylbenz(a) anthracene (DMBA)-induced mammary ...
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The title compound, C(16)H(24)O(3), was synthesized from ilicic acid, which was isolated from the aerial part of Inula viscosa- (L) Aiton [or Dittrichia viscosa- (L) Greuter]. The asymmetric unit contains two independent mol-ecules, in each of which the seven-membered ring shows a chair conformation, whereas the five-membered ring presents disorder. In the two molecules, three C atoms in the fi...
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ژورنال
عنوان ژورنال: IUCrData
سال: 2017
ISSN: 2414-3146
DOI: 10.1107/s2414314617008124